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Not everyone will admit this, but there's something magical about exercise. Your brain produces endorphins in response to vigorous exercise and you feel energized, alert, and alive. You derive tremendous satisfaction from doing something you said you'd do. You feel good about yourself all day long. Beyond these benefits related to personal fulfillment, regular vigorous exercise builds strong muscles and bones and strengthens your cardiopulmonary system. Your heart and lungs become substantially more efficient. Your heart pumps more blood with every beat and your lungs take in more air with every breath. Your entire physiology, that is, every one of your cells, tissues, and organs, benefits from a consistent program of regular exercise.

Yet, remarkably, there's more. Medical researchers and public health policy makers have long known that regular vigorous exercise helps improve the health of people with diabetes, heart disease, many types of arthritis, and even cancer. But more recently, within the last couple of years, scientists have been finding that exercise causes lasting changes in the configuration and functioning of human genes.

As we all know, our genetic inheritance is encoded in complex, tightly wound strands of DNA. Our genetic code comprises only four nucleotides - adenine, thymine, guanine, and cytosine - biochemical structures whose precise sequence contains all the information required to produce a living human being. (Some fun facts: There are approximately 3 billion "base pairs" of DNA in a human cell. A single uncoiled strand of DNA is approximately 3 feet (1 meter) in length. In contrast, human cells average 25 millionths of a meter in diameter.). Up until 10 or so years ago, it was generally accepted that genes (specific sequences of base pairs) controlled all protein formation and all physiologic functioning. But within the last 10 years, numerous discoveries have demonstrated a variety of additional factors that contribute to individual genetic expression. One such mechanism involves "epigenetics", the process of "tagging" genes with small "side groups" or "markers". The attachment of a methyl side group (—CH3), an action known as methylation, modifies a gene's expression, boosting its output or turning it off completely. Researchers have now consistently demonstrated that regular exercise influences and even reprograms the epigenetic pattern of methylation.1,2

One study has demonstrated that exercise-associated methylation patterns impact genes associated with energy metabolism and insulin response in muscles.3 These findings, if reproduced by follow-up studies, would go far toward clarifying the role of exercise in relieving the symptoms of many chronic diseases.

The conclusion is that not only does exercise make you look good and feel good, it also exerts a profound effect on the most basic components of human physiology. Our long-ago high school gym teachers who exhorted us in seemingly endless rounds of sit-ups, push-ups, pull-ups, and squat thrusts knew what they were doing. It's up to us to continue the program.

1Denham J, et al: Exercise: putting action into our epigenome. Sports Med 44(2):189-209, 2014
2Ronn T, et al: A six months exercise intervention influences the genome-wide DNA methylation pattern in human adipose tissue. PLoS Genetics 2013 Jun;9(6):e1003572. doi: 10.1371/journal.pgen.1003572
3Lindholm ME, et al: An integrative analysis reveals coordinated reprogramming of the epigenome and the transcriptome in human skeletal muscle after training. Epigenetics 2014 Dec 7:0. [Epub ahead of print]

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Testimonials

Reviews By Our Satisfied Patients

  • "I love it there so polite and right to the point never pushy or rude vet respectful. I wouldn’t go anyplace else. Love them all!!"
    Kandice Desalvo V.
  • "Dr. Ho and Dr. Q are caring and compassionate doctors. Their goal is to make you feel great. They take the time to listen to your concerns and address them. I would definitely recommend these doctors!"
    Sandra E.
  • "I got refer from a Dear good friend Jennifer which ive been having problems with my neck n knees. I would definitely recommend Pinnacle Wellness they have a great friendly staff n Doctors are great! I've learned a lot about our bodies n etc. I will continue seeing them again !!! My adjustments are great!"
    Cynthia T.
  • "We have been going to Pinnacle Wellness for over 3 months now, back pain has stopped 100%. We are still blown away by how amazing Dr. Q and Dr. Ho are. We are blessed they came into our lives and have truly added so much to our knowledge about our bodies and even personal growth and development. Pinnacle Wellness is nothing short of a breath of fresh air. Isabelle at the front desk always makes our day. If you are looking for a chiropractor that truly cares for your well being, my family would definitely recommend you to look no further and make Pinnacle Wellness your destination. I had just learned to live with and accept my daily back pain. Thanks to Pinnacle Wellness our lives have been forever changed and look forward to seeing the happy faces of the staff and will be enjoying a pain free life thanks to our journey with Pinnacle Wellness."
    Cara C.
  • "If you have back and/or neck trouble and have never been to a chiropractor before, then this is the place for you. I was referred here by my wife who has been seeing the doctors for several years. Since starting my adjustments I sleep better and feel better all around, and no it doesn't hurt. Currently I am recovering from tennis elbow and bursitis which the doctors are helping me recover by using a massager on my arm when I visit, even my physical therapist was glad they were helping out."
    Royce S.
  • "I have been a patient of Pinnacle Wellness for many years. They have a great, friendly staff and Doctors who truly care about there patients. I would recommend this place to anyone with back or neck pain."
    James S.
  • "The staff is extremely friendly and personable when you enter the facility. They make you feel like you are a part of the family. Our kiddos get adjusted too and for our infant it helped him to crawl properly when he was having difficulties or crawling abnormally. It is a vital part of our healthiness and we would recommend them to everyone!"
    Jennifer C.